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Tầng 1, Nhà B2, Đại học Y Hà Nội. Số 1, Tôn Thất Tùng, Đống Đa, HN

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Số 3.2021

VALUE OF PERIPHERAL BLOOD COUNT FOR DENGUE SEVERITY PREDICTION

date12/10/2021 view34

 VALUE OF PERIPHERAL BLOOD COUNT FOR DENGUE SEVERITY PREDICTION

Vu Minh Phuong 1,2, *, Nguyen Hoang Yen 3,

Do Duy Cuong 2.  Pham Quang Vinh 1

1 Hanoi Medical University, 2 Bach Mai Hospital, 3 Saint Paul Hospital

*Corresponding Author: Vu Minh Phuong

Email: vuminhphuong@yahoo.com

Received date: 15/7/2021

Reviewed date: 02/8/2021

Accepted date: 09/8/2021

ABSTRACT

Objective: Dengue virus infection has diverse clinical manifestations often with unpredictable clinical evolution and outcome. This study was to evaluate the value of the peripheral blood cell in association with the severity of Dengue Infection. Method: This was an observational study on 480 adult patients admitted to Bach Mai Hospital (Vietnam) with Dengue illness between August and October 2017. The diagnosis and classification of Dengue were based on WHO 2009 criteria. Blood samples were collected from patients during acute febrile phase time in hospital and the blood cell indices were analyzed. Results: A total 480 patients participated in the study including 223 patients of Dengue without warning signs (A), 212 patients of Dengue with warning signs (B), and 45 patients of severe Dengue (C). B and C were considered as the severe group, and A was classified as the non-severe group. Compared to the non-severe group, the severe group had significantly lowered hemoglobin, WBC, lymphocytes count and percentage of lymphocyte during acute febrile phase on day 5 of illness. The percentage of neutrophil ≥45%, the percentage of lymphocyte <25% was associated with the severe group. Conclusion: The percentage of lymphocytes, percentage of neutrophil are likely to predict for severity. 

Keywords: Peripheral blood count, Dengue with warning signs, severe Dengue

 Tải toàn văn: vui lòng liên hệ và đặt hàng tapchi@sinhlyhoc.com.vn 

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